GABA and Glycine
Both GABA and glycine act as calmatives for nerve impulses and control muscle contractions. GABA is the primary inhibitory neurotransmitter in the brain and regulates other neurotransmissions to prevent overstimulation. Glycine is one of three amino acids needed for the synthesis of creatine, which supplies energy to nerve and muscle cells. Elevated amounts of glycine are found in the muscles, skin and other connective tissues. Glycine is also an inhibitory neurotransmitter, and works much like GABA.
Cramp Bark Powder
Cramp bark powder has long been used to alleviate smooth muscle discomfort. Studies have confirmed that cramp bark promotes a relaxant effect. Herbalists recommend cramp bark for discomfort of either a congestive or spasmodic nature.
Dong Quai Root Extract
A perennial botanical native to China and Japan, Dong quai is effective at easing post-exercise muscle soreness, and has long been used medicinally for smooth muscle tension. Dong quai has active ingredients, called coumarins, which dilate blood vessels, balance the central nervous system and increase blood flow.