TRF 150™ 30 vegetarian capsules

Designs For Health

TRF 150™ and TRF 350™ provide nutritional support for healthy joint function, repair, and relief of occasional inflammation. These products feature Cyplexinol™ PRO, a bone derived protein/collagen complex containing Bone Morphogenetic Proteins (BMPs) and key growth factors naturally contained in bone. This ingredient helps to support the pathways involved in normal bone remodeling, and the proper repair and regeneration of cartilage, thereby supporting good bone health and joint integrity.

To support the activation of bone and cartilage formation 

What is TRF 150™? 
TRF 150™ (Tissue Regeneration Factor) features 150 mg of Cyplexinol®PRO, a bone-derived protein/collagen complex containing Body/Bone Morphogenetic Proteins (BMPs) and key growth factors naturally contained in bone, such as Transforming Growth Factor Beta (TGF-β), Insulin-like Growth Factor (IGF), Platelet Derived Growth Factor (PDGF), and Basic Fibroblast Growth Factor (bFGF).

Applications of TRF 150™

Clinical effects of the results of supplemental BMPs are validated with multiple studies.  TRF 150™ is effective in helping to maintain bone strength and joint homeostasis, as well as the pathways which cause cartilage degradation because it features thoroughly researched Cyplexinol® PRO. The proteins (found in bone and bovine milk) contained in TRF 150™ have been shown to activate the bone and cartilage-forming process. TRF 150™ exerts its effect on bone via increasing bone formation and reducing bone resorption. This allows TRF 150™ to address the processes which lead to cartilage degradation, as well as the ensuing pain and inflammation caused by arthritis and other degenerative joint conditions.  

TRF 150™ should be a first line defense for any stage of osteoporosis, any type of fracture and for any condition in need of joint or cartilage repair.  Consider pairing it with OsteoForce™ (for bones) or ArthroSoothe™ (for joints).

Cyplexinol® PRO studies conclude:

  • Cyplexinol® PRO  is a bone anabolic agent  (tissue regenerating)
  • Bone volume of rats increased by 78% given Cyplexinol® PRO 
  • Promotes bone formation  and reduces bone resorption
  • Improves bone mineral density even in ovariectomized rats
  • Improves bone mass caused by estrogen decline
  • Improves trabecular bone architecture,  trabecular thickness,  and trabecular connectivity
  • Important morphogens with pleiotropic functions

Mechanisms of action:

  • Bone and Cartilage: Osteoinductive effect (stimulating new bone formation)
    Body/Bone Morphogenetic Proteins stimulate mesenchymal stem cells and differentiate them into osteoblasts (produce bone) and chondrocytes (produce cartilage).

Serving Size:
1 capsule

Recommended Use:
As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.

Color, size or shape may appear different between lots.


Does not contain gluten.